백서 임플란트주위염 모델에서 808 nm와 810 nm 파장의 Diode Laser를 이용한 박테리아 제거 효과
Bacteria removal in a SD rat peri-implantitis model using diode laser of 808 nm and 810 nm
김위붕, 이성호, 김륜경, 임호경, 변수환, 임영준, 김성민, 이종호,
소속 상세정보
김위붕 ( Jin Wei-Fung ) - 서울대학교 치과병원 구강악안면외과
이성호 ( Lee Sung-Ho ) - 서울대학교 치과병원 구강악안면외과
김륜경 ( Kim Ryun-Kyung ) - 성균관대학교 정보통신공학과
임호경 ( Lim Ho-Kyung ) - 서울대학교 치과병원 구강악안면외과
변수환 ( Byun Soo-Hwan ) - 동탄한림대학교병원 구강악안면외과
임영준 ( Lim Young-Jun ) - 서울대학교 치과병원 보철과
김성민 ( Kim Soung-Min ) - 서울대학교 치과병원 구강악안면외과
이종호 ( Lee Jong-Ho ) - 서울대학교 치과병원 구강악안면외과
KMID : 1025720160350010001
Abstract
Purpose: Peri-implantitis is defined by an inflammation that occurs at the soft tissue and the alveolar bone around the site of an implant. The failure of implant placement or the loss of the supporting bone may occur due to peri-implantitis. From a pathological perspective, A. actinomycetemcomitans, Capnocytophaga sp., F. nucleatum, or other infectious agent is seen as the cause of the peri-implantitis. To remove the cause of the disease, many non-invasive methods are being studied. In this study, we demonstrated decontamination of the implant surface and its surroundings through experiments using diode laser products in existing products and diode laser experiments that studied the effect on the decreasing peri-implants.
Materials and Methods: 12-week-old male Sprague-Dawley rats weighing 300 g were purchased. The size of 1.2 * 4 mm hole was drilled into the hard plate of the maxillary bone to insert titanium screw implant. Test groups were divided into control, titanium screw implant group, peri-implantitis group, and laser-treated peri-implantitis group. Infection levels around the site of implants were checked with SEM. The degree of microbial reproduction was checked through real-time PCR (qPCR) for each group.
Results: The use of 808 nm Diode laser (0.5 w, 15 seconds in continuous mode) to treat the inflammation caused by peri-implantitis in the soft tissue and the alveolar bone resulted in an effective reduction in the number of bacteria without the surface denaturation of the implant due to the laser. In comparison to the existing products, such as Picaso Diode laser (810 nm) and Bison Diode laser (808 nm), both products have shown effectiveness in eliminating bacteria. In particular, 808 nm Diode laser showed equal effectiveness to the 810 nm Diode laser at a lower temperature.
Conclusion: Peri-implantitis was treated in the inflammation region of soft tissue and alveolar bone using the 808 nm and 810 nm Diode laser in continuous mode at 0.5 w for 15 seconds. As a result, laser-induced excessive heat generation or denaturation on the implant surfaces did not occur and the number of bacteriadecreased.
키워드
808 nm; 810 nm; Diode laser; Peri-implantitis; SD rat; Bacteria
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